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Research Associate, Cell Biology and Biochemistry

COMPANY DESCRIPTION  



Founded in 2016, Foghorn Therapeutics discovers and develops novel drugs to treat cancer and other serious medical disorders. The company seeks to discover novel therapeutics that target chromatin remodeling complexes. Foghorn uses a proprietary platform based on revolutionary advances in the mechanistic understanding of disease.

Summary

We currently seek a highly motivated, creative and collaborative researcher to join our Drug Discovery team in a lab-based role to support early discovery projects in oncology, immuno-oncology and other therapeutic areas.

Responsibilities

  • Develop and optimize cellular and molecular-based assays for screening
  • Support small-scale internal screening 
  • Profile compounds in support of medicinal chemistry efforts
  • Coordinate assay transfer and weekly activity with CROs
  • Evaluate and implement emerging technologies and instrumentation enabling drug discovery
  • Collaboratively work in a multidisciplinary team, analyze and interpret data, prepare summaries and communicate results to project teams

Qualifications

  • BA/BS or MS in Biochemistry, Biology or a related field with 2-6 years of relevant industry experience is required 
  • Cell culture skills and experience with cell-based assays are required
  • Proven ability to work under limited supervision to assess assay performance and optimize assay protocol are required
  • Excellent verbal and written communication skills are required
  • Experience with automated liquid handling instrumentation is a plus
  • High-throughput assay optimization experience is preferred
  • Hands-on experience with fluorescence-based assay techniques (e.g. HTRF, FP, AlphaLISA/AlphaScreen, quench assays) and label-free technologies (e.g. ITC, DSF, SPR, MST) is preferred 
     
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